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Image Search Results
Journal: Bioengineered
Article Title: Sulforaphane protects intestinal epithelial cells against lipopolysaccharide-induced injury by activating the AMPK/SIRT1/PGC-1ɑ pathway
doi: 10.1080/21655979.2021.1952368
Figure Lengend Snippet: Sulforaphane (SFP) protects Caco-2 cells against LPS-induced injury by activating the AMPK/SIRT1/PGC-1ɑ pathway. Cells were exposed for 24 h to LPS (1 μg/mL) and SFP (1 μM) in the presence or absence of a SIRT1 inhibitor (EX527) or PGC-1ɑ inhibitor (SR-18,292). (a) Cell viability. (b) Mitochondrial ROS levels, based on MitoSox dye oxidation. (c) IL-1β levels. Values are mean ± SD (n = 3). * P < 0.05 vs. control group (CN); # P < 0.05 vs. LPS group; $ P < 0.05 vs. LPS+SFP group
Article Snippet: Sulforaphane, the AMPK inhibitor STO-609, the SIRT1 inhibitor EX527, the
Techniques: Control