pgc 1α inhibitor sr 18 292 Search Results


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MedChemExpress pgc 1α inhibitor sr 18 292
Pgc 1α Inhibitor Sr 18 292, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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pgc 1α inhibitor sr 18 292 - by Bioz Stars, 2026-03
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Millipore pgc-1α inhibitor sr-18,292
Sulforaphane (SFP) protects Caco-2 cells against LPS-induced injury by activating the AMPK/SIRT1/PGC-1ɑ pathway. Cells were exposed for 24 h to LPS (1 μg/mL) and SFP (1 μM) in the presence or absence of a SIRT1 inhibitor (EX527) or PGC-1ɑ inhibitor <t>(SR-18,292).</t> (a) Cell viability. (b) Mitochondrial ROS levels, based on MitoSox dye oxidation. (c) IL-1β levels. Values are mean ± SD (n = 3). * P < 0.05 vs. control group (CN); # P < 0.05 vs. LPS group; $ P < 0.05 vs. LPS+SFP group
Pgc 1α Inhibitor Sr 18,292, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/pgc-1α inhibitor sr-18,292/product/Millipore
Average 90 stars, based on 1 article reviews
pgc-1α inhibitor sr-18,292 - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier

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Sulforaphane (SFP) protects Caco-2 cells against LPS-induced injury by activating the AMPK/SIRT1/PGC-1ɑ pathway. Cells were exposed for 24 h to LPS (1 μg/mL) and SFP (1 μM) in the presence or absence of a SIRT1 inhibitor (EX527) or PGC-1ɑ inhibitor (SR-18,292). (a) Cell viability. (b) Mitochondrial ROS levels, based on MitoSox dye oxidation. (c) IL-1β levels. Values are mean ± SD (n = 3). * P < 0.05 vs. control group (CN); # P < 0.05 vs. LPS group; $ P < 0.05 vs. LPS+SFP group

Journal: Bioengineered

Article Title: Sulforaphane protects intestinal epithelial cells against lipopolysaccharide-induced injury by activating the AMPK/SIRT1/PGC-1ɑ pathway

doi: 10.1080/21655979.2021.1952368

Figure Lengend Snippet: Sulforaphane (SFP) protects Caco-2 cells against LPS-induced injury by activating the AMPK/SIRT1/PGC-1ɑ pathway. Cells were exposed for 24 h to LPS (1 μg/mL) and SFP (1 μM) in the presence or absence of a SIRT1 inhibitor (EX527) or PGC-1ɑ inhibitor (SR-18,292). (a) Cell viability. (b) Mitochondrial ROS levels, based on MitoSox dye oxidation. (c) IL-1β levels. Values are mean ± SD (n = 3). * P < 0.05 vs. control group (CN); # P < 0.05 vs. LPS group; $ P < 0.05 vs. LPS+SFP group

Article Snippet: Sulforaphane, the AMPK inhibitor STO-609, the SIRT1 inhibitor EX527, the PGC-1α inhibitor SR-18,292, and LPS were obtained from Sigma (St. Louis, MO, USA).

Techniques: Control